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Effect of 2 Weeks of Time-Restricted Eating on Innate Immunity and Systemic Inflammation in Patients With a History of Myocardial Infarction: A Randomized-Controlled Crossover Study - PubMed

7 hours ago
  • #cardiovascular disease
  • #time-restricted eating
  • #inflammation
  • Study examines the effect of 2 weeks of time-restricted eating (TRE) on innate immunity and systemic inflammation in patients with a history of myocardial infarction.
  • TRE intervention involved eating only between 8 am and 2 pm, compared to a control period with a regular diet.
  • Results showed reduced neutrophil counts, lower neutrophil-to-lymphocyte ratio, and decreased neutrophil CD11b expression with TRE.
  • TRE led to anti-inflammatory changes in the monocyte transcriptome and a reduction in low-grade systemic inflammation.
  • No significant effects were observed on monocyte subsets, inflammatory surface marker expression, or cytokine production capacity.
  • Findings suggest TRE may modulate inflammation and reduce cardiovascular risk in patients with established cardiovascular disease.