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Epidermal PAR2-TRPV3-IL-33 Signaling Promotes Mast Cell Recruitment and Sensory Nerve-Mast Cell Interactions in Atopic Dermatitis - PubMed

4 days ago
  • #dermatology
  • #atopic dermatitis
  • #mast cells
  • The study focuses on epidermal PAR2-TRPV3-IL-33 signaling in atopic dermatitis.
  • This signaling pathway promotes mast cell recruitment in the skin.
  • It also enhances interactions between sensory nerves and mast cells.
  • The research provides insights into the mechanisms of atopic dermatitis.
  • The findings could lead to new therapeutic targets for the condition.