Cellular water-potential sensing through biomolecular condensation - PubMed
2 hours ago
- #water potential sensing
- #plant stress response
- #biomolecular condensation
- Researchers identified SAM8, a protein that condenses in response to water-potential changes, aiding plants in hyperosmotic stress tolerance and seed germination.
- SAM8 is normally hydrated due to a negatively charged patch, preventing condensation; water deficit reduces hydration, triggering condensation through altered molecular interactions.
- SAM8 condensates selectively sequester RNA export factors, leading to nuclear mRNA retention and translational reprogramming under hyperosmotic stress, enabling cellular adaptation to water deficit.