Nobel prize-winning Treg cells in autoimmune kidney diseases and transplantation - PubMed
5 hours ago
- #autoimmune diseases
- #transplantation
- #Treg cells
- The 2025 Nobel Prize in Physiology or Medicine was awarded to Mary E. Brunkow, Fred Ramsdell, and Shimon Sakaguchi for their research on immune system mechanisms preventing autoimmunity.
- Their work led to the discovery of regulatory T cells (Tregs), which play a crucial role in shutting down autoimmunity.
- The article highlights the clinical progress of Treg cell therapies in treating autoimmune kidney diseases and transplant rejection.
- Keywords include CAR Tregs, autoimmunity, cell therapy, regulatory T cells, tolerance, and transplantation.