Mitochondria in situ releasing corosolic acid enhanced antitumor effects via activating mitophagy in castration-resistant prostate cancer - PubMed
6 hours ago
- #Prostate Cancer
- #Organelle-targeted Drug Delivery
- #Mitophagy
- Mitochondria in situ releasing corosolic acid enhances antitumor effects in castration-resistant prostate cancer.
- The mechanism involves activation of mitophagy and generation of reactive oxygen species.
- This study uses an organelle-targeted drug delivery strategy for precise treatment.
- Ethical approval was obtained from the Animal Ethics Committee of Northwestern Polytechnical University (NO. NPU-AE-202301032).
- The authors declare no competing interests.