Curcumin in oral health: mechanisms, clinical evidence, and delivery strategies - PubMed
5 hours ago
- #curcumin
- #oral health
- #anti-inflammatory
- Curcumin, derived from turmeric, has significant therapeutic properties beneficial for oral health, including anti-inflammatory, antioxidant, and antimicrobial effects.
- The review covers curcumin's role in treating various oral diseases such as periodontal diseases, dental caries, oral lichen planus, and oral cancers, with evidence from in vitro studies, animal models, and clinical trials.
- Curcumin shows adjunctive benefits in treatments, comparable to standard therapies in some cases, such as reducing inflammation in periodontal disease and pain in recurrent aphthous stomatitis.
- Various delivery systems like mouthwashes, gels, and nanocarriers have been developed to improve curcumin's bioavailability, though study limitations like small sample sizes and formulation variability exist.
- Curcumin is considered a safe, formulation-dependent adjunct therapy in oral medicine, not a stand-alone treatment, with minimal toxicity or side effects reported.