The Pathophysiology, Mechanism, Diagnosis, and Management of Pulmonary Arterial Hypertension: A Comprehensive Literature Review - PubMed

6 hours ago

Pulmonary arterial hypertension (PAH) is a rare disease group affecting all ages, predominantly young women.
Key disease features include pulmonary arterial remodeling and vasoconstriction, leading to right heart failure.
Common symptoms are shortness of breath and progressive exercise intolerance.
Early diagnosis, identifying the underlying cause, and targeted treatments are crucial for management.
Despite new therapies, PAH remains a high-morbidity and high-mortality condition requiring specialized care.
The study reviews current literature on PAH's pathophysiology, diagnosis, and management.

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