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Patient Characteristics and Clinical Outcomes in a Specialist Hypertension Clinic: A Pragmatic Real-World Single-Center Observational Study - PubMed

18 hours ago
  • #medication adherence
  • #real-world outcomes
  • #hypertension management
  • A retrospective study of 199 patients at a specialist hypertension clinic found significant blood pressure reductions with an average decrease of -13.6/-8.8 mmHg over a median follow-up of 13.8 months.
  • Patients were complex, with 32.7% having secondary hypertension and 17.2% resistant hypertension; BP improvements were consistent across clinical subgroups, including those with diabetes, CKD, and obesity.
  • Medication non-adherence identified via qualitative urine screening in some patients, and targeted interventions led to subsequent BP improvements, highlighting the clinical value of objective adherence assessment.
  • Cardiovascular events were infrequent at 6.5%, but residual cardiovascular risk persisted, indicating that BP control remains challenging despite specialist care.
  • The study advocates for larger multicenter studies with longer follow-up to better define predictors of cardiovascular outcomes and optimize care pathways in hypertension management.