Weight Changes With Tirzepatide and Concomitant Weight-Inducing Medications: Post Hoc Analysis of Randomized Clinical Trials - PubMed
5 hours ago
- #tirzepatide
- #clinical trials
- #weight loss
- Post hoc analysis of SURMOUNT-1, -3, and -4 trials assessed tirzepatide's effect on weight reduction in participants taking weight-inducing (WI) medications.
- Approximately 17-20% of participants across trials used at least one WI medication, with most taking one nonsteroid WI medication.
- Tirzepatide treatment resulted in significant weight loss (-13.3% to -26.1%) compared to placebo, even with concomitant WI medication use.
- The findings suggest that tirzepatide can help achieve clinically meaningful weight reduction in individuals requiring WI medications.