Prognostic Value of Microvascular Resistance Reserve in Coronary Artery Disease: A Systematic Review and Meta-Analysis - PubMed
5 hours ago
- #Risk Stratification
- #Coronary Artery Disease
- #Microvascular Function
- Microvascular Resistance Reserve (MRR) is a novel index for assessing coronary microvascular function independent of epicardial disease.
- Higher MRR is significantly associated with a lower risk of adverse cardiovascular events, with an HR of 0.75 per unit increase.
- Low MRR (dichotomized) confers a more than 2-fold increased risk for major adverse cardiovascular events (HR: 2.39).
- The prognostic effect of MRR is stronger in ST-segment elevation myocardial infarction compared to stable coronary artery disease.
- A threshold of MRR ≥ 3 provides optimal sensitivity and rule-out performance for risk stratification in clinical practice.