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Prevalence and Relative Proportions of Multiple Sclerosis, Neuromyelitis Optica Spectrum Disorder, and Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease in the Republic of Korea - PubMed

14 hours ago
  • #Neuromyelitis Optica Spectrum Disorder
  • #MOGAD
  • #Multiple Sclerosis
  • Study provides nationwide estimates of MS, NMOSD, and MOGAD in Korea.
  • Total of 4,196 patients identified: 1,799 MS, 1,616 NMOSD, and 781 MOGAD.
  • Ratio of MS:NMOSD:MOGAD is 2.3:2.1:1.
  • Mean age at onset varies: MS (33.4 years), NMOSD (42.7 years), MOGAD (41.7 years).
  • Female-to-male ratios: MS (2.2:1), NMOSD (5.1:1), MOGAD (1.5:1).
  • Crude prevalence estimates per 100,000: MS (3.48), NMOSD (3.13), MOGAD (1.51).
  • Findings reflect a distinctive Korean CNS inflammatory demyelinating disease profile.
  • Higher proportion of NMOSD and MOGAD due to low MS prevalence in East Asia.