Safety and efficacy of direct versus conventional transfer to angiography suite in patients with severe acute stroke treated with thrombectomy (DIRECT ANGIO) in France: a multicentre, open-label, blin
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- #stroke
- #randomised controlled trial
- #thrombectomy
- Study compared direct transfer to angiography suite (DTAS) vs conventional pathway for severe acute stroke patients.
- Multicentre, open-label, randomised controlled trial in France with 115 participants.
- Primary outcome: functional independence at 90 days; safety outcomes included symptomatic intracranial haemorrhage and mortality.
- DTAS group showed increased risk of symptomatic intracranial haemorrhage (15% vs 0%).
- No significant difference in all-cause mortality or functional independence between groups.
- Trial stopped early for safety reasons, limiting precision of effect estimates.
- Further trials needed to confirm safety and efficacy of DTAS for acute ischaemic stroke.