The use of oXiris hemofilter in the initial continuous renal replacement therapy among patients with septic shock: A propensity score matched analysis - PubMed
4 hours ago
- #Hemoadsorption
- #Septic Shock
- #CRRT
- Study compares oXiris hemofilter vs. M100 in initial CRRT for septic shock.
- Propensity score matched analysis of 69 patients in each group.
- oXiris showed longer 28-day vasopressor-free days (24 vs. 19, p=0.04).
- oXiris had shorter CRRT duration (72 vs. 117 hours, p=0.03).
- Greater SOFA score reduction with oXiris (-2 vs. 1, p=0.004).
- Competing risk analysis found no significant difference in vasopressor weaning.
- No significant differences in lactate, PCT, IL-6, fluid balance, LOS, or mortality.
- Unadjusted analyses suggest potential benefits, but not confirmed by primary outcome analysis.
- Cautious interpretation required; prospective studies needed for definitive conclusions.