Postoperative Urinary Retention After Reversal of Neuromuscular Block by Neostigmine versus Sugammadex in Patients Undergoing Laparoscopic Cholecystectomy: A Randomized Controlled Trial - PubMed
5 days ago
- #Laparoscopic Cholecystectomy
- #Neuromuscular Blockade Reversal
- #Postoperative Urinary Retention
- Study compares postoperative urinary retention (POUR) incidence after reversal of neuromuscular blockade with neostigmine versus sugammadex in laparoscopic cholecystectomy patients.
- 235 patients received rocuronium for neuromuscular blockade, reversed with either sugammadex or neostigmine/glycopyrrolate.
- POUR incidence was significantly lower with sugammadex (12.8% difference, P < .001) compared to neostigmine.
- No major adverse events reported in either group.
- Sugammadex provides a significant reduction in POUR without major adverse effects, supporting its use in fast-track surgery protocols.