Cardiovascular outcomes of GLP-1RA vs SGLT2i in MASLD and type 2 diabetes: real-world evidence - PubMed
2 days ago
- #Cardiovascular outcomes
- #GLP-1RA
- #MASLD
- Study compares cardiovascular outcomes of GLP-1RA vs SGLT2i in patients with MASLD and type 2 diabetes.
- GLP-1RA use associated with lower risk of major adverse cardiovascular and cerebrovascular events compared to SGLT2is.
- Lower risks of heart failure, myocardial infarction, stroke, and all-cause mortality observed with GLP-1RA.
- Results consistent across sensitivity analyses, supporting GLP-1RA's cardiovascular benefits in this population.
- Study utilizes real-world evidence and target-trial emulation principles to reduce biases.