High-resolution nuclear cell biology by cryo-electron tomography - PubMed
4 hours ago
- #nuclear biology
- #chromatin
- #cryo-electron tomography
- The nucleus is a dynamic organelle involved in transcription, replication, ribosome biogenesis, and nucleocytoplasmic transport.
- Cryo-electron tomography (cryo-ET) provides high-resolution, three-dimensional views of nuclear architecture in situ.
- Cryo-ET has reshaped understanding of chromatin organization, nuclear pore complex dynamics, and chromatin-lamina interactions.
- It resolves biological debates and links nuclear structure to function, bridging molecular and cellular scales.