High-Intensity Interval Training Boosts Immune Cells in Advanced Cancer Patients and Healthy Controls: Implications for Cancer Care - PubMed
6 hours ago
- #Immune Cell Mobilization
- #Cancer Care
- #High-Intensity Interval Training
- A single HIIT session significantly increased circulating total NK cells immediately post-exercise in both advanced cancer patients and healthy controls, with increases of 50% and 38% respectively.
- Circulating innate lymphoid cells (cILCs) increased significantly during exercise in both groups, with median within-subject increases of 21% in patients and 55% in controls.
- After the initial increase, NK cell counts decreased significantly during the recovery period, dropping by 43% in patients and 69% in controls.
- Immune cell responses correlated with training heart rate in both groups, and additionally with BMI in healthy controls and age in patients for specific subsets.
- The study demonstrates that acute HIIT is feasible for advanced cancer patients undergoing chemotherapy and can transiently mobilize key immune cells, suggesting potential implications for cancer care.