Tropism and Replication Competence of Cattle Influenza A(H5N1) Genotype B3.13 Virus in Human Bronchus and Lung Tissue - PubMed
21 hours ago
- #zoonotic transmission
- #respiratory infection
- #influenza
- Influenza A(H5N1) genotype B3.13 viruses emerged from cattle in 2024, causing mild human spillover infections.
- Study used human bronchus and lung tissue to assess tropism, replication, and pathogenesis of two cattle influenza isolates.
- Viruses demonstrated moderate replication competence and triggered robust proinflammatory responses.
- Findings indicate potential risks to human health from these cattle-origin H5N1 viruses.