Nutritional Status in Obesity: A Comprehensive Narrative Review of Dysbiosis, Micronutrient Deficiencies and the Effects of Probiotics/Synbiotics - PubMed
5 hours ago
- #gut microbiota
- #obesity
- #probiotics
- Obesity is a chronic disease associated with comorbidities like type 2 diabetes and dyslipidemia.
- Intestinal dysbiosis (imbalance in gut microbiota) is common in obesity and contributes to metabolic complications.
- Obesity often involves deficiencies in essential vitamins and minerals, worsening metabolic and inflammatory dysfunctions.
- Gut microbiota in individuals with obesity differs from healthy individuals, with altered Firmicutes/Bacteroidetes ratios and reduced diversity.
- Antibiotic use can worsen dysbiosis, impair energy metabolism, and promote inflammation, exacerbating obesity.
- Probiotics and synbiotics are promising for managing metabolic disorders by restoring microbiota balance and improving weight-related conditions.
- This narrative review explores gut microbiota alterations in obesity, their impact on nutritional deficiencies, and the role of probiotics.