Recommended Medical Investigations in Pediatric Acute-Onset Neuropsychiatric Syndrome - PubMed
7 hours ago
- #neuropsychiatric
- #pediatrics
- #PANS
- The study evaluates the clinical utility of recommended laboratory and medical investigations for children with Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS).
- Participants included 109 children (51 with PANS and 58 with idiopathic OCD/tic disorders as controls) aged 4-18 years from Stockholm, Sweden.
- Nearly all participants had at least one abnormal laboratory finding, with no significant differences between PANS and control groups.
- Most PANS participants had 3+ abnormal findings, while controls had 4+; only one PANS case was diagnosed with celiac disease.
- The study questions the clinical utility of comprehensive medical investigations for PANS due to frequent nonactionable findings and lack of diagnostic yield.