Exploration of the proxiOME of large subunit ribosomal proteins reveals Acl1 and Bcl1 as cooperating dedicated chaperones of Rpl1 - PubMed
6 hours ago
- #dedicated chaperones
- #ribosomal proteins
- #nuclear import
- Exploration of large subunit ribosomal proteins in yeast reveals Acl1 and Bcl1 as dedicated chaperones for Rpl1.
- Acl1 and Bcl1 form a trimeric complex with Rpl1, enabling its nuclear import and shielding its rRNA-binding surface.
- Proximity labeling identified novel interactions between ribosomal proteins and importins, plus transient associations of chaperones with pre-ribosomal particles.