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Renal Outcomes in People With HIV-1 and Renal Impairment Treated With Bictegravir/Emtricitabine/Tenofovir Alafenamide: Integrated Analysis From 9 Phase 3/3b Clinical Trials - PubMed

4 hours ago
  • #HIV-1
  • #B/F/TAF
  • #Renal Impairment
  • Integrated analysis of 9 phase 3/3b clinical trials involving 1069 people with HIV-1 and mild to moderate renal impairment.
  • Participants were treated with bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF) over up to 240 weeks.
  • Renal function remained generally stable throughout the follow-up period.
  • Renal adverse events were infrequent, and discontinuation due to renal toxicity was rare.