Sex-Specific Associations Between Depression and Cardiovascular-Kidney-Metabolic Syndrome Progression: A National Cohort Study - PubMed
4 days ago
- #Cardiovascular-Kidney-Metabolic Syndrome
- #Sex-specific health
- #Depression
- Depressive symptoms are linked to cardiovascular-kidney-metabolic (CKM) syndrome progression, particularly in women.
- The study involved 5,035 participants aged 45 and older, with 53.2% being women.
- Women had higher baseline depressive symptom scores compared to men (8.0 vs. 6.0 on the CESD-10 scale).
- CKM progression occurred in 33.5% of women and 31.5% of men over a 4-year follow-up.
- A significant positive association between depressive symptoms and CKM progression was found in women (adjusted OR 1.12 per 5-point increase).
- No significant association was observed in men (adjusted OR 1.00 per 5-point increase).
- Women with high depressive symptoms had a 35% higher risk of CKM progression compared to those with low symptoms.
- The findings suggest psychological interventions could help delay CKM progression, especially in women.