A paradigm of the diagnosis and treatment for the whole process of Alzheimer's disease - PubMed
4 hours ago
- #Alzheimer's disease
- #diagnostic framework
- #sequential therapy
- The article proposes a new diagnostic and therapeutic paradigm for Alzheimer's disease (AD) aimed at improving whole-process management.
- Diagnosis integrates core clinical criteria, early-changing biomarkers, syndrome staging, and TCM pattern phenotyping to enhance correlation with clinical severity.
- Treatment involves a sequential, stage-adaptive plan using dynamic, multi-target combination therapy tailored to disease progression, unlike static single-target approaches.
- This paradigm seeks to improve translational relevance, clinical applicability, and continuity of care, requiring future cohort-based validation for confirmation.