Cardiac rehabilitation against frailty and sarcopenia in older individuals: a literature review - PubMed
5 hours ago
- #sarcopenia
- #cardiac rehabilitation
- #frailty
- Frailty and sarcopenia are common in older adults with cardiovascular disease (CVD), leading to reduced functional capacity and poorer quality of life.
- Shared pathophysiological pathways include chronic inflammation, hormonal decline, oxidative stress, and mitochondrial dysfunction, accelerating muscle loss and disability.
- Physical activity and cardiac rehabilitation (CR) are key therapeutic strategies, with resistance training improving strength and functional performance.
- Conventional CR may not suit all patients; adapted interventions like bodyweight training or electrical muscle stimulation are beneficial for certain conditions (e.g., post-transcatheter aortic valve implantation).
- Personalized, multidisciplinary approaches are needed to overcome barriers, alongside further research to refine diagnostics and optimize long-term outcomes.