Inflammatory signalling in diabetic cardiomyopathy: molecular mechanisms and potential therapeutic strategies - PubMed
5 hours ago
- #diabetic cardiomyopathy
- #inflammation
- #therapeutic strategies
- Diabetic cardiomyopathy is a complication of diabetes mellitus, driven by hyperglycemia and hyperlipidemia.
- Chronic inflammation plays a key role in diabetic cardiomyopathy, involving pro-inflammatory cytokines, chemokines, and immune cell activation.
- Persistent hyperglycemia and hyperlipidemia exacerbate inflammatory processes, impairing cardiac function.
- No current treatments reverse diabetic cardiomyopathy; strategies focus on delaying or halting disease progression.
- Potential therapeutic strategies target inflammatory signaling pathways to treat diabetic cardiomyopathy.