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Exercise induces sex-specific assembly of mitochondrial supercomplexes - PubMed

5 days ago
  • #sex-specific adaptation
  • #mitochondrial supercomplexes
  • #exercise physiology
  • Exercise induces sex-specific changes in mitochondrial supercomplex assembly in skeletal muscle.
  • Males show increased assembly of complex III into high molecular weight supercomplexes with exercise intensity.
  • Females maintain stable levels of both high molecular weight and I+III2 supercomplexes during exercise.
  • Assembly of complex IV into supercomplexes is not affected by exercise in either sex.
  • The study involved healthy young subjects performing moderate- and high-intensity exercise bouts.