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The effectiveness of non-invasive positive pressure ventilation combined with rehabilitation training in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis - Pu

3 days ago
  • #COPD
  • #NPPV
  • #Pulmonary Rehabilitation
  • Non-invasive positive pressure ventilation (NPPV) combined with pulmonary rehabilitation (PR) improves exercise capacity, dyspnea, and respiratory muscle strength in COPD patients.
  • Meta-analysis of 17 RCTs (489 participants, mostly GOLD stage III-IV) showed significant improvements in 6-minute walk distance, shuttle walk test, oxygen uptake, and respiratory muscle pressures.
  • NPPV + PR reduced blood lactate levels, BORG dyspnea score, and mMRC scale but did not significantly affect quality of life.
  • NPPV is a valuable adjunct to PR for COPD patients with exercise limitations.