Association of vitamin D and N-acetylcysteine supplementation with anxiety, cognition, and biomarkers in generalized anxiety disorder: a retrospective cohort study - PubMed
5 hours ago
- #vitamin-D
- #N-acetylcysteine
- #anxiety-disorder
- Study investigates vitamin D and NAC supplementation in GAD patients.
- 88 patients divided into observation (vitamin D3 + NAC + usual care) and control (usual care only) groups.
- Assessed anxiety, cognition, and biomarkers at baseline and week 8.
- Observation group showed greater improvements in BAI, ATQ, and DAS scores.
- Favorable biomarker changes in observation group: increased 25(OH)D, GSH, SOD, BDNF, DA, 5-HT, NE; decreased MDA, IL-6, hs-CRP.
- Low and similar adverse event rates in both groups.
- Combined supplementation associated with better outcomes than usual care alone.