Microbial transformation of secondary bile acids: roles in gut ecology and autoimmune diseases - PubMed
5 hours ago
- #gut microbiota
- #autoimmune diseases
- #secondary bile acids
- Secondary bile acids (SBAs) are important regulators of gut microbial ecology and immune responses.
- Advancements in AI and mass spectrometry have revealed a diverse SBA pool, with hundreds identified and thousands of enzymes predicted.
- Multi-omics studies confirm SBAs' role in autoimmune disease pathogenesis.
- SBAs' functions are closely tied to their molecular structures, influencing gut microbiota and immune homeostasis.