Vitamin D deficiency, multimorbidity, and mortality in stage 2 cardiovascular-kidney-metabolic (CKM) Syndrome: evidence from the NHANES 2001-2018 cohort - PubMed
6 hours ago
- #Multimorbidity
- #Vitamin D deficiency
- #CKM syndrome
- Study compares mortality risks in stage 2 CKM syndrome patients across different multimorbidity states.
- Investigates if sufficient vitamin D (≥75 nmol/L) modulates the link between multimorbidity and mortality.
- Data from NHANES 2001-2018 cohort involving 12,406 patients, with 913 all-cause and 223 CVD deaths.
- Higher multimorbidity groups (2-4) showed significantly increased all-cause and CVD mortality risks.
- Sufficient vitamin D levels may reduce mortality risks, especially for CVD, in stage 2 CKM patients.
- Findings suggest maintaining adequate vitamin D could mitigate mortality risks linked to multimorbidity progression.
- Plain language summary highlights higher death risks in CKM patients with multiple chronic conditions.
- Adequate vitamin D levels (≥75 nmol/L) associated with lower mortality risks in multimorbid CKM patients.
- Study suggests vitamin D assessment and management could be important in early CKM syndrome care.
- Further research needed to determine if vitamin D supplementation directly improves survival outcomes.