European Consensus Guidelines on the Management of Respiratory Distress Syndrome - 2025 - PubMed
3 days ago
- #Respiratory Distress Syndrome
- #Guidelines
- #Neonatology
- Seventh version of European Guidelines for the Management of RDS based on literature up to mid-2025.
- Emphasis on collaboration with obstetricians for preterm delivery risk prediction and perinatal optimization including antenatal steroids.
- Delivery room protocols include maintaining normal body temperature, promoting spontaneous breathing, and using non-invasive respiratory support.
- Early use of surfactant via thin catheter to avoid intubation is recommended.
- Lung protective strategies for mechanical ventilation to reduce bronchopulmonary dysplasia risk.
- Prenatal management focuses on confirming preterm labor for judicious use of antenatal steroids.
- Physiological based cord clamping suggested over time-based clamping in the delivery room.
- Starting FiO2 of 0.6 recommended for infants born < 29 weeks' gestational age to reduce bradycardia.
- Surfactant prophylaxis reappears for extremely preterm infants with emphasis on videolaryngoscopy for LISA.
- Nasal ventilation preferred over CPAP for non-invasive respiratory support post-stabilization and weaning.
- Treatment thresholds for FiO2 remain at 0.3, with ultrasound recommended for RDS diagnosis regardless of FiO2.