The hybrid preclinical ecosystem: a strategic roadmap for oncology R&D - PubMed
4 hours ago
- #preclinical models
- #translational research
- #oncology R&D
- Regulatory, economic, and pandemic-related challenges are reducing the dominance of animal models in biomedical research.
- Advances in human-derived systems like tumor organoids and computational models enable more human-relevant studies in oncology.
- A hybrid preclinical ecosystem is emerging, integrating human-specific data with refined animal validation to de-risk clinical translation.