Function and regulation of the mitochondrial stress response - PubMed
5 days ago
- #therapeutics
- #stress response
- #mitochondria
- Mitochondria play crucial roles in metabolism and signaling, requiring continuous monitoring and adjustment.
- A conserved stress response detects and alleviates challenges to mitochondrial integrity.
- Recent studies show mitochondrial stress triggers coordinated protective reactions to preserve the organelle.
- The review discusses components, coordination, and control within the mitochondrial stress response.
- Understanding mitochondrial stress signaling is informing therapeutic approaches for diseases with high unmet needs.
- M.R. has multiple affiliations with therapeutic companies, while other authors declare no competing interests.