Cerebral small vessel disease imaging markers and disease severity in moyamoya disease: Insights from magnetic resonance imaging analysis - PubMed
17 hours ago
- #Cerebral Small Vessel Disease
- #Moyamoya Disease
- #MRI Imaging
- Cerebral small vessel disease (CSVD) imaging markers were significantly higher in moyamoya disease (MMD) patients compared to healthy controls, including asymptomatic cases.
- Factors independently associated with severe CSVD burden in MMD include older age, hemorrhage, infarction, advanced Suzuki stage (≥4), and high platelet-lymphocyte ratio.
- The summary CSVD score strongly correlates with MMD disease severity, as shown by a high area under the curve (AUC = 0.809).
- CSVD imaging markers are effective indicators for assessing MMD severity and progression, especially in older patients and those with ischemic symptoms.