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Combined diagnostic value of rheumatoid arthritis-specific citrullinated protein, haemoglobin-to-red cell distribution width ratio, and anti-CCP antibody in rheumatoid arthritis - PubMed

4 hours ago
  • #Diagnostic Markers
  • #Rheumatoid Arthritis
  • #Haematological Indicators
  • The study explores the clinical significance of new haematological indicators (RA-CP, HRR, MPV/PC) in rheumatoid arthritis (RA).
  • RA-CP and HRR were identified as independent predictors of RA, with RA-CP as a risk factor and HRR as a protective factor.
  • Combined detection of RA-CP, HRR, and anti-CCP antibody significantly improved diagnostic accuracy and sensitivity (AUC = 0.998, sensitivity = 98.31%).
  • MPV/PC did not show significant independent predictive value in this study, marking the first exploration of its potential role in RA.
  • The study analyzed data from 700 subjects, including RA patients, other autoimmune disease patients, and healthy controls.