Aging Can Spread Through Your Body via a Single Protein, Study Finds
8 days ago
- #aging
- #biomedical research
- #cellular senescence
- ReHMGB1 protein identified as a key driver in spreading aging signals through the bloodstream.
- ReHMGB1 triggers cellular senescence, permanently disabling cells and sending damaging signals systemically.
- Blocking ReHMGB1 in mice improved muscle regeneration, physical performance, and reduced signs of aging.
- Study suggests potential for developing treatments to slow aging by controlling ReHMGB1 signals.
- ReHMGB1 also has beneficial roles in alerting biological systems to damage, complicating potential interventions.
- Research highlights the complexity of aging, with many factors contributing to lifespan and health decline.
- Findings published in Metabolism, pointing to future research directions for aging-related therapies.