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KDM5B-driven glucose metabolic reprogramming promotes enzalutamide resistance in prostate cancer via the lactate/hnRNPA1 lactylation/AR-V7 axis - PubMed

4 hours ago
  • #KDM5B
  • #Prostate Cancer
  • #Enzalutamide Resistance
  • KDM5B-driven glucose metabolic reprogramming promotes enzalutamide resistance in prostate cancer.
  • The resistance mechanism involves the lactate/hnRNPA1 lactylation/AR-V7 axis.
  • Study approved by the Medical Ethics Committee of the First Affiliated Hospital of Chongqing Medical University.
  • No competing interests declared by the authors.