A photoreceptor state links aggressive brain tumors in children - PubMed
5 hours ago
- #developmental vulnerability
- #photoreceptor signature
- #brain tumors
- Group 3 medulloblastoma, pineoblastoma, and retinoblastoma share a common tumor-associated photoreceptor signature.
- The shared signature is rooted in transient developmental progenitors.
- This research reframes these cancers as diseases of common developmental vulnerability.
- Identifies shared transcriptional dependencies with potential therapeutic relevance.