An NLR-transposase fusion gene from rye provides broadly effective resistance to stripe rust in wheat - PubMed
5 days ago
- #wheat resistance
- #stripe rust
- #NLR-transposase fusion
- Stripe rust, caused by Puccinia striiformis f. sp. tritici, is a major threat to global wheat production.
- A resistance gene named Yr83 was identified on chromosome 6RL in rye, providing near-immunity and broadly effective resistance to stripe rust in transgenic wheat.
- Yr83 encodes an atypical NLR protein fused to a Harbinger transposase-derived nuclease domain (HTDND), which is essential for immune function.
- Phylogenetic analysis showed NLR-HTDND proteins are restricted to the Pooideae subfamily.
- A small 6RL translocation line was developed for breeding, showing strong resistance and improved agronomic traits like spikelet and grain number per spike.
- The study highlights the potential of transposase-integrated NLR genes for wheat stripe rust resistance breeding.