Is Alzheimer's an Autoimmune Disease? - PubMed
5 hours ago
- #Alzheimer's disease
- #Neurodegenerative disorder
- #Autoimmune hypothesis
- Alzheimer's disease is a progressive neurodegenerative disorder affecting cognitive and functional abilities.
- Primary pathological factors include amyloid-β plaques and neurofibrillary tangles with hyperphosphorylated tau.
- Emerging evidence suggests some Alzheimer's variants may involve an autoimmune process.
- The paper reviews evidence for and against the autoimmune hypothesis of Alzheimer's disease.
- Keywords include Astrocytes, Autoantibodies, Blood-brain barrier, Immunotherapy, Infectious agents, and Microglia.