Conduction System Pacing for Cardiac Resynchronization Therapy - A Systematic Review - PubMed
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- #Conduction System Pacing
- #Cardiac Resynchronization Therapy
- #Systematic Review
- Biventricular pacing (BVP) is the standard for CRT in heart failure with LBBB, but it is non-physiological and has limitations like anatomical constraints and non-responders.
- Conduction system pacing (CSP), including His bundle pacing and left bundle branch area pacing, is a more physiological alternative for CRT that may offer superior ventricular synchrony.
- Large-scale randomized trials on CSP are lacking, and challenges with procedural complexity and long-term data prevent it from being first-line over BVP currently.
- This review synthesizes existing CSP literature, explores its clinical applications, and discusses ongoing controversies and future prospects.