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Hypertensive Disorders of Pregnancy and Premature Cardiovascular Disease in a Diverse Cohort of Young US Women - PubMed

5 days ago
  • #Cardiovascular Disease
  • #Women's Health
  • #Hypertensive Disorders of Pregnancy
  • Hypertensive Disorders of Pregnancy (HDP) are linked to increased risk of premature cardiovascular disease (CVD) in young US women.
  • The study used data from the All of Us research program, analyzing over 17,000 women from diverse backgrounds.
  • HDP was associated with a 1.82 times higher risk of CVD, independent of prepregnancy cardiometabolic risk factors.
  • Women without prepregnancy risk factors had a higher CVD risk (aHR 2.06) compared to those with risk factors (aHR 1.33).
  • Findings were replicated in an independent cohort, confirming the association between HDP and CVD.
  • The study highlights the need for integrating pregnancy complications into CVD risk assessments to mitigate early-onset CVD in women.