Herpesvirus Retinitis by Immune Status: Clinical Phenotypes and Predictors of Retinal Detachment and Severe Visual Impairment - PubMed
5 hours ago
- #visual outcomes
- #retinal detachment
- #herpesvirus retinitis
- The study evaluated clinical manifestations, retinal detachment patterns, treatments, and visual outcomes in herpesvirus retinitis, identifying predictors for RD and severe visual impairment.
- Among 120 patients with ARN or CMVR, CMVR was more common in immunocompromised patients with lymphoma, while ARN was more unilateral, peripheral, and fulminant.
- ARN led to earlier and more frequent retinal detachment, with ARN and worse baseline vision being independent risk factors for RD.
- Surgical intervention and concurrent RD were linked to reduced odds of severe visual impairment, with PCR-based analyses confirming similar patterns.
- Host immune status defined distinct clinical phenotypes, highlighting the importance of early recognition and tailored management strategies.