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Maternal 12-HETE is associated with childhood asthma and the responses to prenatal omega-3 supplementation - PubMed

7 hours ago
  • #prenatal supplementation
  • #childhood asthma
  • #respiratory health
  • Maternal 12-HETE deficiency is linked to increased childhood asthma and respiratory infections.
  • Undetectable maternal plasma 12-HETE during pregnancy alters infant airway microbiota and immune profile.
  • Higher prenatal n-3 LCPUFA exposure reduces asthma and infections in mothers with detectable 12-HETE.
  • Maternal 12-HETE may serve as a biomarker for offspring respiratory morbidity risk.
  • 12-HETE status could determine responsiveness to prenatal n-3 LCPUFA supplementation.