Sleep alters neurovascular and hydrodynamic coupling in the human brain - PubMed
5 hours ago
- #neurovascular coupling
- #sleep
- #CSF flow
- Sleep enhances cerebrospinal fluid (CSF) solute transport, aiding brain tissue homeostasis.
- Infraslow vasomotion, CSF flow, and electrophysiological potential increase during sleep.
- Functional MRI, EEG, and near-infrared spectroscopy were used to study these changes in healthy volunteers.
- During wakefulness, electrophysiological potential and water concentration changes predict hemodynamic BOLD changes.
- During sleep, interactions between signals become more bidirectional, losing net directionality.
- Nonneural processes like vasomotor-driven hydrodynamic waves gain more impact on brain activity during sleep.