Incidence of Adverse Events in Peripheral Intravenous Vasopressor Use: A Systematic Review and Meta-Analysis - PubMed
5 hours ago
- #meta-analysis
- #vasopressors
- #critical care
- Peripheral intravenous (PIV) vasopressor use is associated with low incidence of adverse events (AEs).
- The study is a systematic review and meta-analysis focusing on AEs and central venous catheter (CVC) avoidance in critically ill adults.
- Minor AE incidence varied by vasopressor type: norepinephrine (2.6%), epinephrine (0.0%), phenylephrine (2.9%), dopamine (1.4%), vasopressin (0.5%), and metaraminol (0.9%).
- Major AEs were rare, with venous thromboembolism occurring in 1.4% of midline catheter cases and only one tissue necrosis event in short PIV catheters.
- CVC avoidance was achieved in 59.7% of cases, suggesting PIV vasopressors can reduce the need for CVC placement with proper monitoring.