The Effects of Remimazolam Tosylate on Postoperative Memory Function in Young and Middle-Aged Patients Undergoing Laparoscopic Surgery - PubMed
5 hours ago
- #Laparoscopic Surgery
- #Postoperative Memory
- #Remimazolam
- Remimazolam tosylate compared to propofol reduced early postoperative memory decline in young and middle-aged patients after laparoscopic surgery.
- The remimazolam group showed lower levels of IL-6 and S100β, indicating a milder inflammatory response and reduced neural injury markers.
- Patients receiving remimazolam experienced more stable hemodynamics with fewer episodes of hypotension and bradycardia compared to propofol.
- No significant difference was observed in the incidence of postoperative cognitive dysfunction (POCD) at one month between the two groups.
- Risk factors for early memory decline included lower education, diabetes, propofol use, and longer anesthesia duration.