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Rising energetic cost of walking predicts cognitive impairment - PubMed

4 hours ago
  • #Alzheimer's disease
  • #cognitive impairment
  • #walking efficiency
  • The study examines the link between the rising energetic cost of walking and cognitive impairment in older adults.
  • 687 cognitively normal older adults (mean age 74.0 ± 7.2 years, 52% women) were followed over 7.6 ± 3.8 years with repeated walking energy expenditure assessments.
  • 91 participants (13%) developed cognitive impairment, showing a steeper increase in walking energy cost compared to non-progressors.
  • Higher baseline energetic cost predicted cognitive impairment in adults aged ≥75 years but not in those aged 65-74.
  • Walking efficiency is suggested as a physiological link between mobility and cognitive health, potentially reducing the risk of Alzheimer's disease and related dementias.