Independent effects of whey protein and alkali supplementation on muscle health in healthy older adults: factorial randomized controlled trial - PubMed
6 hours ago
- #muscle health
- #nutritional supplements
- #older adults
- The study investigated the effects of whey protein (WP) and alkali (KHCO3) supplementation on muscle health in healthy older adults aged ≥65 years.
- Participants were assigned to one of four groups: WP plus KHCO3, WP plus placebo-KHCO3, placebo-WP plus KHCO3, or double placebo, in a 2x2 factorial design.
- Primary outcomes included double leg press muscle power, physical performance, lean mass, muscle mass, and serum IGF-1 levels, measured at baseline and after 24 weeks.
- Results showed no significant improvement in muscle power, physical performance, or muscle mass with either WP or KHCO3 supplementation compared to their respective placebos.
- However, both WP and KHCO3 supplementation led to higher serum IGF-1 levels compared to their placebos.
- The study concluded that neither WP nor KHCO3 supplementation improved muscle health measures in healthy older adults with adequate protein intake, despite increased IGF-1 levels.